Cellcyclearrest相关论文
Glioblastoma multiforme(GBM)is the most malignant and lethal primary brain tumor in adults accounting for about 50%of all......
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Marsdenia tenacissima extract induces G0/G1 cell cycle arrest in human esophageal carcinoma cells by
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In vitro antitumor effect of cucurbitacin E on human lung cancer cell line and its molecular mechani
Cucurbitacin E (CuE) is previously reported to exhibit antitumor effect by several means.In this study,CuE acted as a ty......
Metabolites tested by 14.7T high-resolution proton magnetic resonance spectroscopy can potently asse
Objective To investigate the relationship between DNA damage which was considered enhancing apoptosis and metabolites af......
Naringenin Induces Cell Cycle Arrest and Apoptosis in pancreatic cancer Cells via PI3K/Akt/mTOR Sign
Objective Pancreatic cancer,the fourth most common cause of cancer-related deaths,is one of the most aggressive and deva......
Matrine inhibits the growth and induces apoptosis of osteosarcoma cells in vitro by inactivating the
Matrine,a natural product,has been demonstrated to be a promising chemotherapeutic drug for some cancers.Usingflowcytome......
Apigenin and Abivertinib,a novel BTK inhibitor synergize to inhibit Diffuse large B-cell lymphoma in
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目的 Lung squamous cell carcinoma(LSQCC)is the second-largest histological subtype of lung cancer,which is the leading c......
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Isophilippinolide A Arrests Cell Cycle Progression and Induces Apoptosis in Human Melanoma Cells for
Three new butanolides, isophilippinolide A, philippinolide A, philippinolide B, an amide, cinnaretamine were isolated fr......
Androgen-independent LNCaP cell is a more aggressive phenotype subline of LNCaP cell and growth supp
Androgen deprivation therapy (ADT,surgical or chemical castration) is the mainstay treatment for metastatic PCa,but pati......
Fine particulate matters inducing reproductive impairment by causing cell cycle arrest and activatin
Fine particulate matters(PM2.5)have been associated with male reproductive toxicity,but the underlying mechanism is uncl......
Atorvastatin increase CRPC radiosensitivity via depressing intracellular ROS metabolism and cell cyc
Poor radiosensitivity is accompanied with castrate resistant prostate cancer (CRPC) progression, a few articles reported......
A novel oral camptothecin analog,gimatecan,exhibits superior antitumor efficacy than irinotecan towa
Objective Esophageal squamous cell carcinoma cancer(ESCC)is one of the most frequently diagnosed and deadly malignancy w......
Burkitts lymphoma(BL)is a highly aggressive non-Hodgkins lymphoma,with remarkable cell proliferation and metabolism.The ......
Objective: To study the effect of Arctigenin on human breast cancer cells in vitro and its possible influencing mechanis......
Endosulfan induced cell cycle arrest via the Notch signaling pathway and damaging the cytoskeleton i
Our previous study showed that endosulfan could trigger the extrinsic coagulation pathway via damaging endothelial cells......
Aim Chronic myelogenous leukemia (CML) is a hematopoietic stem cell cancer caused by the BcrAbl tyrosine kinase which ar......
HIV protease inhibitors sensitize human head and neck carcinoma cells to radiation by activating end
Aim Head and neck cancers are the eighth most common cancer worldwide.Despite significant advances in the delivery of tr......
Purpose: Compounds of Ophiopogon japonicas have medicinal effects including anti-inflammatory and anticancer effects.In ......
Chikusetsusaponin IVa Methyl Ester Induces G1 Cell Cycle Arrest, Triggers Apoptosis and Inhibits Mig
Purpose: Panacis Japonici Rhizoma(PJR)is one of the most famous Chinese medical herbs and presents potential anti-cancer......
Methylophiopogonanone B,a microtubule destabilizing agent,causes mitotic arrest and potentiates apop
Objective: Compounds isolated from Ophiopogon japonicas have been reported to present medicinal effects including anti-i......
Objective To investigate the molecular mechanism of endosulfan reproductive toxicity.Methods The GC-lspg cells were expo......
The previous studies have showed that endosulfan has adverse effects on male reproductive system and the oxidative stres......
ATM-mediated Chk1/2 and Cdc2 phosphorylation is Involved In Jaridonin-induced cell cycle arrest In h
Aims: Jaridonin, a novel diterpenoid from Rabdosia rubescens has been shown previously to inhibit proliferation of esoph......
Direct Effects of 125I Seeds Radiation on A549 Lung Cancer Cells:G2/M Arrest and Enhanced Cell Death
Introduction External beam radiation (EBRT) and 125I seed continuous low dose rate radiation (CLDR)were used to treat pa......
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Chemotherapy remains a common treatment for cancer in humans,but its effects are limited.It has been reported that iridi......
Retroviral vector containing human p16 gene and its inhibitory effect on Bcap-37 breast cancer cells
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面对各种因素导致的DNA损伤,细胞有一套应答修复机制。其中细胞周期阻滞在DNA损伤应答修复中扮演了重要角色,为修复受损DNA创造了条......
作为开发新型有效抗癌药物的进一步工作,采用分子杂交策略和路易斯酸催化偶联反应设计合成了一系列新型喹啉-吲哚类化合物.使用噻......
Endosulfan inhibited the start and process of meiosis via depression of Sohlh1 expression and G2M ph
Abstract : Endosulfan is a persistent organic pollutant and widely used in agriculture as a pesticide.To investigate......
Endosulfan induced cell cycle arrest and proliferation inhibition via the Notch signaling pathway in
To investigate the molecular mechanism of endosulfan damaging endothelial cell, human umbilical vein endothelial cel......
Cell Cycle Perturbations Induced by Human Herpesvirus 6 Infection and Their Effect on Virus Replicat
In eukaryotic cells, cell growth and division occur in a stepwise, orderly fashion described by a process known as t......
Methylophiopogonanone B,a microtubule destabilizing agent,causes mitotic arrest and potentiates apop
Objective: Compounds of Ophiopogon japonicas have been reported to have medicinal effects including anti-inflammator......
Endosulfan inhibited the meiosis process by controlling the start of meiosis and causing spermatogen
The previous studies have showed that endosulfan induced male reproductive toxicity and oxidative stress is related ......
Synergistic effect of cell differential agent-Ⅱ and arsenic trioxide on induction of cell cycle arre
AIM: To illustrate the possible role of cell differential agent-Ⅱ (CDA-Ⅱ) in the apoptosis of hepatoma cells induced b......
Inhibitory effect of tumor suppressor p33ING1b and its synergy with p53 gene in hepatocellular carci
AIM: To investigate the inhibitory effect of tumor suppressor p33ING1b and its synergy with p53 gene in hepatocellular c......
α-Mangostin and apigenin induced the necrotic death of BT474 breast cancer cellswith autophagy and i
Objective: To find new compounds in order to overcome the mainstay of metastatic breast cancer due to the adverse side e......
Remarkably Reduced Expression of FoxO3a in Metaplastic Colorectum,Primary Colorectal Cancer and Live
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Total Triterpenoids from Ganoderma Lucidum Suppresses Prostate Cancer Cell Growth by Inducing Growth
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Gambogic acid induces mitochondria-dependent apoptosis by modulation of Bcl-2 and Bax in mantle cell
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Diffuse large B-cell lymphoma(DLBCL)is the most common type of non-Hodgkin lymphoma,char-acterized by high heterogeneity......